MM 500 Mixer Mill Vario
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MM 500 Mixer Mill Vario

Processing 2 to 50 samples in one batch

The new Mixer Mill MM 500 vario is a versatile bench-top unit which provides ultimate performance with maximum flexibility for your sample preparation process.

It is used for dry, wet and cryogenic grinding of small sample amounts with high throughput. The MM 500 vario can be equipped with screw-top grinding jars from 1.5 ml to 50 ml. Available materials include hardened steel, stainless steel, tungsten carbide, agate, zirconium oxide, PTFE.

For biological applications such as homogenization of plant materials, tissues or for cell disruption via bead beating, the MM 500 vario can be equipped with different adapters for single-use vials from 0.2 – 5 ml.

MM 500 MIXER MILL VARIO INTRODUCTION

THE STRONG MIXER FOR HIGH THROUGHPUT APPLICATIONS

  • Max. speed 35 Hz
  • Horizontal oscillation causes strong impact effects for effective sample processing
  • Up to 8 mm feed size and 5 µm final fineness
  • 6 grinding stations for jars of min. 2 ml and max. 50 ml, adapter holds up to 50 x 2 ml single use vials
  • Steel jars can be precooled manually in liquid nitrogen
  • Bench-top model, touch screen, storable SOPs and cycle programs, 7 different jar materials

PERFORMANCE AND DESIGN

  • Grind sizes down to 5 μm possible
  • Powerful pulverization with up to 35 Hz
  • Twice as fast as mills with only 30 Hz
  • Ergonomic design with touch display

FLEXIBILITY

  • Suitable for dry, wet or cryogenic grinding
  • Equally suited for rapid (<2 min) and long-term grinding (up to 99 hours)
  • 12 SOPs and 4 program cycles with max. 99 repeats facilitate routine applications
  • Grinding jars of various sizes and materials; adapters for single-use vials 

SOLUTIONS FOR BIOGICAL APPLICATIONS AND CELL DISRUPTION

Mixer mills are widely used for homogenizing biological samples such as tissue, liver, muscle, plants, corn or sputum. For cell disruption via bead beating mixer mills are also the perfect solution. The MM 500 vario accommodates adapters for different single-use vials:

0.2 ml / 1.5 ml / 2 ml / 5 ml

Depending on the tube and the type of adapter, 5-10 tubes can be inserted per adapter, resulting in the following maximum vial capacity per batch:

50 x 1.5 or 2 ml (or 60 x 0.2 ml)
20 x 5 ml

Typical grinding / homogenizing processes of biological materials take less than 2 min. Cell disruption with a good reproducibility and efficiency takes 20 sec to 5 min, depending on the cell type. Cryogenic grinding in single-use vials can also be a suitable way to pulverize tough or temperature-sensitive samples.

MAXIMIZE YOUR THROUGHPUT

  • Maximum frequency of 35 Hz reduces grinding time to 50% compared to mixer mills with only 30 Hz
     
  • Six grinding stations instead of two, as in classic mixer mills, ensure high throughput
     
  • In combination, the throughput of the MM 500 vario is 6 times higher compared to a classic mixer mill
Grinding of basalt in the MM 500 vario results in better fineness compared to classic Mixer Mills thanks to the increased frequency of 35 Hz instead of 30 Hz (50 ml jar + 12 x 12 mm grinding balls).

ACCESSORIES FOR THE MM500 VARIO

FOR SAFE AND EFFECTIVE GRINDING PROCESSED

GRINDING JARS IN 6 DIFFERENT MATERIALS

All grinding jars of the smaller MM 400 model are compatible with the MM 500 vario. The nominal volume ranges from 1.5 ml to 50 ml and available materials include hardened steel, stainless steel, agate, tungsten carbide, zirconium oxide and PTFE, ensuring contamination-free sample preparation.

ADAPTERS FOR SINGLE-USE VIALS

The adapters for 0.5 / 1.5 / 2 / 5 ml single-use vials of the smaller MM 400 model can be used in the MM 500 vario.

TYPICAL SAMPLE MATERIALS

RETSCH mixer mills are true allrounders. They homogenize, for example, waste, soil, chemical products, coated tablets, drugs, ores, grain, tissue, glass, hair, ceramics, bones, plastics, alloys, minerals, oil seeds, plants, sewage sludge, pills, textiles, wool etc.

Concrete
Wood
Plastic
Hair

FUNCTIONAL PRINCIPAL

The grinding jars of the mixer mill MM 500 vario perform radial oscillations in a horizontal position. The inertia of the grinding balls causes them to impact with high energy on the sample material at the rounded ends of the grinding jars and pulverize it. Also, the movement of the grinding jars combined with the movement of the balls result in the intensive mixing of the sample. The degree of mixing can be increased even further by using several smaller balls.

TECHNICAL DATA

Applications mechanochemistry, homogenization, size reduction, cryogenic grinding, mechanical alloying, mixing,
Field of application agriculture, biology, chemistry / plastics, construction materials, engineering / electronics, environment / recycling, food, geology / metallurgy, glass / ceramics, medicine / pharmaceuticals
Feed material hard, medium-hard, soft, brittle, elastic, fibrous
Size reduction principle impact, friction
Material feed size* <= 8 mm
Final fineness* ~ 5 µm
Batch size / feed quantity* max. 6 x 20 ml
No. of grinding stations 6
Vibrational frequency 3 – 35 Hz (180 – 2100 min-1)
Typical mean grinding time 30 s – 2 min
Dry grinding yes
Wet grinding yes
Cryogenic grinding yes
Cell disruption with reaction vials yes
Self-centering clamping device yes
Type of grinding jars screw top design
Material of grinding tools hardened steel, stainless steel, tungsten carbide, zirconium oxide, agate, PTFE
Grinding jar sizes 1.5 ml / 5 ml / 10 ml / 25 ml / 35 ml / 50 ml
Setting of grinding time digital, 10 s – 8 h
Total grinding time 99 h
Storable SOPs 12
Number of storable cycle programs 4 (with 99 repeats)
Electrical supply data 100-120 V, 50/60 Hz; 200-230 V, 50/60Hz
Power connection 1-phase
Protection code IP 30
Power consumption 750 W
W x H x D closed 690 x 375 x 585 mm
Net weight ~ 60 kg
Standards CE

*depending on feed material and instrument configuration/settings

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